When the embryo is allowed to grow for 5 days and transfered into the uterus after aspiration of the ocyte
By definition, a blastocyst is a highly differentiated, highly developed embryo that is ready to attach to the uterine wall. This attaching is also known as “implantation.”
Only 20 to 30 percent of the fertilised eggs develop into blastocysts at all. If an embryo reaches this stage, there is a higher chance of implantation.
The chances of getting pregnant after blastocyst transfer are very high. Compared to embryo transfer at day 2 or 3 the odds are increased by around 7% . In women up to the age of 30, the chance of success is between 45 and 50 percent, and for women aged 30-39 it is between 35 and 40 percent. However, blastocyst culture does not provide the same advantages for all women. Those with a low egg count and quality may indeed benefit from a day-3 transfer, in which the embryos are inserted in the mother’s uterus at an earlier stage. It therefore goes without saying that our reproductive medicine specialists will work together with you to determine the best transfer method for you as part of a ‘personalised, individual medical approach’, thus striving for the best possible chance of success for you.
The key characteristic of the blastocyst is that it has reached the point where the developing baby’s own genes have been activated and take over the remainder of the development. This is known as “genomic activation,” and because genes are the chemical codes that make us unique individuals, genomic activation is the key point at which a unique individual results from conception.
As the embryos which grow to day 5 , most probably will be genetically healthy and the chances of pregnancy increases , multiple pregnancies have gone down since we have started blastocyst transfer as only one healthy embryo is transferred back in the uterus.
The embryos which grow to a blastocyst are tested for any abnormalities by pre genetic testing {pgs} day 5 embryos biopsy is performed and the genetical material is sent for testing The healthy embryo is only tansfered
Not always in a low diminished egg reserve where the embryos are pooled in The patient goes for 2 cycles of egg retrival the embryos formed are transferred on day3 and have got results. So every case is individualised and treated accordingly
Many papers have been produced where they compared day 3 versus blastocyst transfer Blastocyst transfer has a higher cumulative pregnancy rate Hence most of the centers prefer a blastocyst transfer
Dr Nikita lad is an IVF Specialist and a Fertility Preserving Surgeon, she has helped many cancer patients. She is a Director of Baby4 Real IVF at Juhu and Head and Chief IVF Consultant at Apollo Fertility, Belapur, Navi Mumbai.
She is practicing IVF since 18+ years and has helped more than thousands of patients achieve their dream of becoming parents.
Dr Nikita Lad had done her MBBS from K J Somaiya College, Mumbai and Post Graduation from Sion Hospital, throughout her education she received many awards and accolades.
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